J Genomics
2021; 9:26-37.
doi:10.7150/jgen.53019 This volumeCite
Research Paper
Analysis of Genome Sequences of Coagulase-Negative Staphylococci Isolates from South Africa and Nigeria Highlighted Environmentally Driven Heterogeneity
Tawanda Elias Maguvu✉, Adegboyega Oyedele Oladipo, Cornelius Carlos Bezuidenhout
Unit for Environmental Sciences and Management: Microbiology, North-West University, Potchefstroom, South Africa. Private Bag X6001, Potchefstroom, 2520, South Africa
✉ Corresponding author: Tawanda Elias Maguvu (temaguvucom)
Citation:
Maguvu TE, Oladipo AO, Bezuidenhout CC. Analysis of Genome Sequences of Coagulase-Negative Staphylococci Isolates from South Africa and Nigeria Highlighted Environmentally Driven Heterogeneity. J Genomics 2021; 9:26-37. doi:10.7150/jgen.53019. https://www.jgenomics.com/v09p0026.htm
Here, we report high-quality annotated draft genomes of eight coagulase-negative staphylococci (CoNS) isolates obtained from South Africa and Nigeria. We explored the prevalence of antibiotic resistance and virulence genes, their association with mobile genetic elements. The pan-genomic analysis highlighted the environmentally driven heterogeneity of the isolates. Isolates from Nigeria had at least one gene for cadmium resistance/tolerance, these genes were not detected in isolates from South Africa. In contrast, isolates from South Africa had a tetM gene, which was not detected among the isolates from Nigeria. The observed genomic heterogeneity correlates with anthropogenic activities in the area where the isolates were collected. Moreover, the isolates used in this study possess an open pan-genome, which could easily explain the environmentally driven heterogeneity.
Maguvu, T.E., Oladipo, A.O., Bezuidenhout, C.C. (2021). Analysis of Genome Sequences of Coagulase-Negative Staphylococci Isolates from South Africa and Nigeria Highlighted Environmentally Driven Heterogeneity. Journal of Genomics, 9, 26-37. https://doi.org/10.7150/jgen.53019.
ACS
Maguvu, T.E.; Oladipo, A.O.; Bezuidenhout, C.C. Analysis of Genome Sequences of Coagulase-Negative Staphylococci Isolates from South Africa and Nigeria Highlighted Environmentally Driven Heterogeneity. J. Genomics 2021, 9, 26-37. DOI: 10.7150/jgen.53019.
NLM
Maguvu TE, Oladipo AO, Bezuidenhout CC. Analysis of Genome Sequences of Coagulase-Negative Staphylococci Isolates from South Africa and Nigeria Highlighted Environmentally Driven Heterogeneity. J Genomics 2021; 9:26-37. doi:10.7150/jgen.53019. https://www.jgenomics.com/v09p0026.htm
CSE
Maguvu TE, Oladipo AO, Bezuidenhout CC. 2021. Analysis of Genome Sequences of Coagulase-Negative Staphylococci Isolates from South Africa and Nigeria Highlighted Environmentally Driven Heterogeneity. J Genomics. 9:26-37.
This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.