J Genomics 2022; 10:45-48. doi:10.7150/jgen.69822 This volume

Research Paper

Complete Genome Sequence of Four Strains of Leptospira borgpetersenii serovar Hardjo isolated from Cattle in the Central United States

Ellie J. Putz, Darrell O. Bayles, David P. Alt, Jarlath E. Nally

Infectious Bacterial Disease Research Unit, USDA Agriculture Research Service, National Animal Disease Center, Ames, IA, USA.

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Citation:
Putz EJ, Bayles DO, Alt DP, Nally JE. Complete Genome Sequence of Four Strains of Leptospira borgpetersenii serovar Hardjo isolated from Cattle in the Central United States. J Genomics 2022; 10:45-48. doi:10.7150/jgen.69822. Available from https://www.jgenomics.com/v10p0045.htm

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Abstract

Graphic abstract

Pathogenic species of Leptospira cause leptospirosis, a global zoonotic disease affecting humans and all major livestock species. Cattle act as a reservoir host for L. borgpetersenii serovar Hardjo which colonize the kidneys and reproductive tract from which they are excreted and transmitted to other cattle via urine, semen or uterine discharges. Bovine leptospirosis results in reproductive failure, abortion, stillbirth and loss of milk production, and is an occupational risk for those working with infected animals. A recent study determined that 7.2% of cattle from an abattoir in the central United States were actively shedding pathogenic Leptospira. Here, we report and compare the complete genome sequence of four recent isolates of L. borgpetersenii serovar Hardjo designated strain TC112, TC147, TC129, and TC273.

Keywords: Leptospira borgpetersenii, leptospirosis, bovine, PanOCT/PanACEA