J Genomics 2019; 7:14-17. doi:10.7150/jgen.31170
Short Research Communication
Genome Sequencing and Annotation of Bacillus subtilis UBBS-14 to Ensure Probiotic Safety
Center for Research and Development, Unique Biotech Limited, Hyderabad - 500 078, India
Sulthana A, Lakshmi SG, Madempudi RS. Genome Sequencing and Annotation of Bacillus subtilis UBBS-14 to Ensure Probiotic Safety. J Genomics 2019; 7:14-17. doi:10.7150/jgen.31170. Available from http://www.jgenomics.com/v07p0014.htm
Bacillus subtilis is a rod shaped, gram positive, spore producing bacterium. They are the normal flora of gastrointestinal tract of humans and it is the best characterized model organism for endospore formation. It has the ability to withstand environmental stress, and synthesize beneficial compounds, therefore, it is recognized as a high-quality probiotic supplement. To ensure the probiotic safety and the efficiency, we report the whole genome sequence (WGS) of Bacillus subtilis UBBS-14 strain. The draft genome sequence of Bacillus subtilis UBBS-14 consists of 4,048,984 bp and 4,017 genes, respectively. Bacillus subtilis UBBS-14 does not carry any antibiotic resistant genes containing plasmid, nor it contains any harmful putative virulence factors coding genes, therefore, it confirms the probiotic safety of the respective strain at genome level.