J Genomics 2015; 3:97-98. doi:10.7150/jgen.13910

Short Research Communication

Draft Genome of Multidrug-Resistant Klebsiella pneumoniae 223/14 Carrying KPC-6, Isolated from a General Hospital in Malaysia

Norazah Ahmad1#, Teik Min Chong2#, Rohaidah Hashim1, Surianti Shukor1, Wai-Fong Yin2, Kok-Gan Chan2 ✉

1. Bacteriology Unit, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia
2. Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia.
# Both authors contributed equally.

Abstract

We performed whole genome sequencing on a clinical multidrug-resistant Klebsiella pneumoniae strain 223/14. Investigation into its draft genome revealed the presence of KPC-6 variant, suggesting carbapenemase is present in this isolate. We found a plasmid-borne KPC gene (882 bp) inserted between two transposase genes in the genome of K. pneumoniae 223/14.

Keywords: Klebsiella pneumoniae Carbapenemase (KPC), multidrug resistance, whole genome sequencing

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How to cite this article:
Ahmad N, Chong TM, Hashim R, Shukor S, Yin WF, Chan KG. Draft Genome of Multidrug-Resistant Klebsiella pneumoniae 223/14 Carrying KPC-6, Isolated from a General Hospital in Malaysia. J Genomics 2015; 3:97-98. doi:10.7150/jgen.13910. Available from http://www.jgenomics.com/v03p0097.htm